Settin et al (2014) researched the link between mutations in the MTHFR genes and the susceptibility for and complications of Type 2 Diabetes Mellitus (T2DM).

Results showed those with the 677TT and 1298AA mutations were more susceptible to T2DM. Furthermore, these mutations were also found to be risk factors for heart disease and diabetic neuropathys (damage to the nervous system due to high blood sugar).

Article Here