Read some of our latest news and articles here at MTHFR
Histadelia vs. Histapenia
Histadelia vs. Histapenia: Does the Pfeiffer protocol always make sense? Understanding Your Histamine Blood Test Results Histamine is most popularly known for its role in allergic and inflammatory processes, including immediate and delayed hypersensitivity immune
Histamine and Mental Health
Histamine and Mental Health How Histamine Imbalance Could be Ruining Your Mood One of the many functions of histamine in the body is to act as a neurotransmitter, where it helps regulate important brain functions
HNMT Cofactors and Inhibitors
Histamine Intolerance Histamine intolerance (HIT) is a relatively common condition. The occurrence of HIT is increasing more these days, although the actual mechanism is not completely resolved. When it comes to HIT, we always think
HER-stamine? The Link Between Histamine and Estrogen
HER-stamine? The Link Between Histamine and Estrogen The female hormone estrogen may play a role in the development of histamine intolerance. This seems plausible since women consist of the majority who suffer from this. One
How does histamine effect our brain and nervous system?
How does histamine effect our brain and nervous system? Histamine is a natural substance produced by the human body and is a substance with many important functions. Histamine was first isolated in 1907 by Windaus
Role of 5-methyltetrahydrofolate (5-MTHF) in Cardiovascular Disease
Role of 5-methyltetrahydrofolate (5-MTHF) in Cardiovascular Disease Cardiovascular disease is a major health concern. Multiple co-morbidities are responsible for increasing the cardiovascular risks some of which include hypercholesterolemia, diabetes, smoking and hypertension.  All these
DAO Deficiency and Histamine: The Unlikely Connection
DAO Deficiency and Histamine: The Unlikely Connection What does it mean? We live in a time when we can choose what to eat. But in our endeavour to be healthy, what are we doing to
Role of Vitamin B12 in Pregnancy Related Obesity
Role of Vitamin B12 in Pregnancy Related Obesity You are B12 deficient when your serum B12 is <150 pmol/l according to our Australian Labs. But the reality is that this number is way too low
Histamine and Gut Health: The unlikely connection between allergies and our own gut microbes.
Histamine and Gut Health – The unlikely connection between allergies and our own gut microbes. If you think the role of histamine is only in allergy and allergic reactions, you’re quite mistaken. Don’t worry, it’s
Step 2 in MTHFR Support: How To Choose The Right B12 For You
We’ve written plenty about the importance of B12 intake with regards to the MTHFR gene. The best sources of B12 will always be the food you eat (specially meat) but what if you need to
Step 1 in MTHFR Support: 10 Health Tips For Those With Deficiencies
Step 1 in MTHFR Support – 10 Health Tips For Those With Deficiencies Make sure you’ve read our article on MTHFR so you’ll have a little background on this mutation. What is Methylation? Methylation is
Histamine Intolerance 101: That Innocent Meal May Not Be So Innocent After All
Histamine Intolerance 101: That Innocent Meal May Not Be So Innocent After All Headaches, itching, puffy eyes, hives, cough, and palpitations – if you are suffering from one or more of these symptoms, and you’re
Histamine and Methylation
Histamine and Methylation Histamine Histamine is a hydrophilic vasoactive amine derived from histidine through carboxylation by L-histidine decarboxylase1. Histamine, once formed, can be stored or rapidly undergo deamination or demethylation, which is catalyzed by diamine
Functional Benefits of Hydroxocobalamin Supplements
Hydroxocobalamin is a precursor to methylcobalamin and Vitamin B12. It is usually prescribed in conditions where B12 cannot be properly absorbed in the gut. It is manufactured naturally as a therapeutic agent with the help
Methylcobalamin, also referred to as MeB12 and MeCbl, is a member of the cobalamin family and is one of the naturally occurring coenzyme forms of cobalamin found in the human body. Structurally, Methylcobalamin exists in
Are You Suffering From B12 Deficiency?
Are You Suffering From B12 Deficiency? I believe one of the most overlooked deficiencies in Australia, and probably worldwide, is B12 deficiency. Our reference ranges are too low and so people don’t really notice when they’re B12
B12 Insufficiency and Folate – a Crucial Factor in Pregnancy
B12 Insufficiency and Folate – a Crucial Factor in Pregnancy We already know that vitamin B12, or cobalamin, is an essential nutrient for pregnancy, because it is important for cell growth and baby development. Specifically,
Risks of Folic Acid and Excessive Folate Intake in Pregnancy
Risks of Folic Acid and Excessive Folate Intake in Pregnancy We learned previously that there are differences between folic acid and methyl folate when they are taken by pregnant women. New scientific studies reveal more
Upregulated methylation increases expression and proliferation of cancer cells??
Upregulated methylation increases expression and proliferation of cancer cells??? There is no question that the future of medicine will be in analysing a person’s genetics, with a detailed family history and addressing the genetic inefficiencies
Endocrine Disruptors, Health & Fertility: How They’re Affecting You
Endocrine Disruptors, Health & Fertility: How They’re Affecting You Is your home filled with hormone, MTHFR and fertility friendly products? Endocrine Disruptors (ED) are a group of synthetic, man-made chemicals that have permeated many/most aspects
Bisphenol A: Why It’s Bad and How to Avoid It
Bisphenol A: BPA or Bisphenol A is a common chemical found in plastics and has been in large scale industrial use since the 1960’s. This chemical is found primarily in two substances – polycarbonate plastics and
Prenatal Folate and Homocysteine Affect Children’s IQs
Prenatal Folate and Homocysteine Affect Children’s IQs Folate is important for the overall methylation and synthesis of DNA, which is critical to your baby’s development. But it’s particularly essential for the growth and replication of
Neural Tube Defects Linked to MTHFR & COMT Genes
Neural Tube Defects Linked to MTHFR & COMT Genes Anencephaly, spina bifida and encephalocele are the most common types of Neural Tube Defects (NTD’s), and develop due to the failure of the neural tube to
MTHFR Gene Test Now Available!
MTHFR Gene Test Now Available! MTHFR Support Australia is excited to announce we now offer MTHFR gene testing, carried out by integrative and functional pathology centre NutriPath. The test is a blood spot test,
Let’s Review Using Folic Acid Supplements in Fertility Treatments
Let’s Review Using Folic Acid Supplements in Fertility Treatments In my current series of preconception webinars I am not surprised by the number of women joining me who have had multiple miscarriages or who are
Join our FREE 10-Day ‘MTHFR in Preconception’ Email Course!
Join our FREE 10-Day ‘MTHFR in Preconception’ Email Course! In line with our current focus on MTHFR in preconception, our founder and MTHFR expert Carolyn Ledowsky has been busy creating and hosting our FREE
Key Blood Tests for Preconception Nutrition
Key Blood Tests for Preconception Nutrition Key Blood Tests for Preconception Nutrition As you may know, one of the primary nutrients needed for a healthy pregnancy is folate (Vitamin B9), due to it’s vital role
Top 20 Folate Containing Foods
Top 20 Folate Containing Foods While MTHFR gene mutations can inhibit the conversion of folate you eat (dihydrofolate) into the active folate (5-MTHF), is it still vitally important to consume as much natural
Could MTHFR be the Reason for your Pregnancy Complications?
Could MTHFR be the Reason for your Pregnancy Complications? While the list of disorders associated with MTHFR mutations can be a long and eye-opening one, those conditions involving pregnancy or the ability to fall pregnant
Why is MTHFR important in preconception and pregnancy?
Why is MTHFR important in preconception and pregnancy? One of the most common things I hear is the utter confusion many people find themselves in after they: Just discovered the MTHFR gene and fell down
Top 5 Action Steps for MTHFR in Preconception
Top 5 Action Steps for MTHFR in Preconception: Are you wondering how your MTHFR result may influence your ability to fall pregnancy, affect your pregnancy or the health of your future child? Here are is
The lies and misinformation about MTHFR Gene in Preconception & Pregnancy ￼
The Lies and Misinformation about MTHFR Gene in Preconception & Pregnancy You know I get really annoyed about the misinformation being spread to people surrounding the MTHFR gene in preconception and pregnancy. I can’t
SNP Learning with Sterling Hill
Join Sterling Hill , Carolyn Ledowsky and Cynthia Smith on the SNP Learning Masterclass. For a unique insight into Sterling’s variant report. A must for all practitioners wanting an insight into Methylation. SNP_learning_series_ 2015,final SNP Learning
Letter to Claire Harvey
On the weekend, journalist Claire Harvey wrote an article about naturopaths. Not only was it ill founded, disparaging and downright ridiculous, but I would have expected a journalist of her background to present a more
American Heart Association should re-think their status on MTHFR mutations
Recently Stephan Moll and Elizabeth Varga wrote on Homocysteine and MTHFR Mutations in this months American Heart Association journal, while much of the information about homocysteine is accurate, its relationship to MTHFR mutations and Cardiovascular risk
The MTHFR and Vaccination Debate !!
The MTHFR and Vaccination Debate! Should Children with MTHFR Deficiency Receive Scheduled Vaccinations? The Australian government and its public health organization announces that under the changes to the Public Health Act 2010, child care
Folic Acid vs 5-MTHF in Treating MTHFR Deficiency
Folic Acid vs 5-MTHF in Treating MTHFR Deficiency Carolyn Ledowsky Founder MTHFR Support Australia Download PDF Folic Acid vs 5-MTHF Over the course of this year, there have been many articles about the
The folic acid vs 5-MTHF debate.
Over the course of this year, there have been many articles about the benefits of folic acid vs L-5MTHF here in Australia and I think the writings have been somewhat one sided, so I have
Vitamin B12 – The Reference Range Level is Set too Low
As a statement made by one of the leaders in vitamin B12 field more than 10 years ago, Carmel’s idea of “cobalamin deficiency should not be diagnosed unless megaloblastic changes are found’ is
Apps, Sulphur and do you have Pyroluria? Findings from the MABIM Conference
By Carolyn Ledowsky The Chemical Heritage Foundation recently played host to the MABIM Conference. I travelled to Philadelphia, USA to attend the two day conference in order to gain a more thorough understanding of how
We Have Moved
We have moved to beautiful new premises in Neutral Bay. Please update our contact details to: Address: MTHFR Support Australia Suite 9, Level 1 20 Young St Neutral Bay, NSW, 2089 Mailing Address: PO Box 1265 Neutral
We are excited to announce MTHFR Support Australia is moving premises in January 2015! From Monday 5th January 2015, we will be expanding and relocating to our our new premises in Neutral Bay, Sydney, Australia. Please
The Methylation Myths: MTR & MTRR
Following on from the first post in our series addressing why methylfolate is NOT necessarily the answer to a patient’s MTHFR mutation, this week we look at the B12 balance in reference to the MTR
PODCAST: Interview with Dr Ben Lynch
Last week Carolyn was lucky enough to spend some time interviewing one of the leading authorities in the world of MTHFR, Dr Ben Lynch – the founder of mthfr.net and Seeking Health. Dr Ben is
Practitioner Know How – The Methylfolate Myths
Welcome to the first post in our methylfolate ‘know how’ series The Methylfolate Trap Did you know that the answer to a positive MTHFR mutation may not be methyfolate? In fact you could actually be
Is MTHFR affecting your heart health?
23.3 million, that’s a big number! …by 2030 more than 23 million people will die annually from cardiovascular disease (CVD) (World Health Organisation) Cardiovascular disease is already the number one cause of death globally, with
PODCAST: Interview with Sterling Hill
Last week Carolyn was lucky enough to spend some time talking with Sterling Hill, the founder of MTHFRSupport.com. It is Sterling’s App (accessed via mthfrsupport.com) from which we generate the 23andMe reports analysed by Carolyn
Depression and MTHFR
The Link Between Depression and MTHFR Media attention has increased lately with the acknowledgement that high profile celebrities like Ian Thorpe and Charlotte Dawson have suffered greatly with depression. We have to ask ourselves why
Welcome to MTHFR Support Australia!
From Carolyn and the team at MTHFR Support Australia, welcome to our website! We are soon to be launching regular podcasts and webinars, and will continue to bring you the latest research. But for now?